The response of premature infants to infection with type 3 attenuated poliovirus

Joseph S. Pagano; Stanley A. Plotkin; Donald Cornely

doi:10.1016/S0022-3476(64)80517-5

The response of premature infants to infection with type 3 attenuated poliovirus

Joseph S. Pagano, Stanley A. Plotkin, Donald Cornely

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Shortly after birth premature infants are highly susceptible to infection with the Fox type 3 attenuated poliovirus except in the presence of the highest titers of transplacentally acquired antibodies, and the majority of the infants, despite their immaturity, are able to respond to this antigenic stimulus by forming readily detectable titers of virus neutralizing antibodies.

Original language	English (US)
Pages (from-to)	165-175
Number of pages	11
Journal	The Journal of pediatrics
Volume	65
Issue number	2
DOIs	https://doi.org/10.1016/S0022-3476(64)80517-5
State	Published - Aug 1964

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(64)80517-5

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title = "The response of premature infants to infection with type 3 attenuated poliovirus",

abstract = "Shortly after birth premature infants are highly susceptible to infection with the Fox type 3 attenuated poliovirus except in the presence of the highest titers of transplacentally acquired antibodies, and the majority of the infants, despite their immaturity, are able to respond to this antigenic stimulus by forming readily detectable titers of virus neutralizing antibodies.",

author = "Pagano, {Joseph S.} and Plotkin, {Stanley A.} and Donald Cornely",

note = "Funding Information: Biology and The Philadelphia General Hospital, Philadelphia, Pa. This investigation was supported, in part, by Grant E-1799 from the National Institute of Allergy and Infectious Diseases, United States Public Health Service.",

year = "1964",

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doi = "10.1016/S0022-3476(64)80517-5",

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AU - Pagano, Joseph S.

AU - Plotkin, Stanley A.

AU - Cornely, Donald

N1 - Funding Information: Biology and The Philadelphia General Hospital, Philadelphia, Pa. This investigation was supported, in part, by Grant E-1799 from the National Institute of Allergy and Infectious Diseases, United States Public Health Service.

PY - 1964/8

Y1 - 1964/8

N2 - Shortly after birth premature infants are highly susceptible to infection with the Fox type 3 attenuated poliovirus except in the presence of the highest titers of transplacentally acquired antibodies, and the majority of the infants, despite their immaturity, are able to respond to this antigenic stimulus by forming readily detectable titers of virus neutralizing antibodies.

AB - Shortly after birth premature infants are highly susceptible to infection with the Fox type 3 attenuated poliovirus except in the presence of the highest titers of transplacentally acquired antibodies, and the majority of the infants, despite their immaturity, are able to respond to this antigenic stimulus by forming readily detectable titers of virus neutralizing antibodies.

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The response of premature infants to infection with type 3 attenuated poliovirus

Abstract

ASJC Scopus subject areas

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