The replication of kinetoplast DNA

P. T. Englund, J. C. Marini

Research output: Contribution to journalArticlepeer-review

Abstract

Kinetoplast DNA is the mitochondrial DNA of trypanosomatids. This DNA consists primarily of thousands of small minicircles which are linked together to form a giant network. Replication of this DNA involves release of individual minicircles from the network to form free minicircles. The free minicircles then replicate and the two progeny are reattached to the network. When all minicircles within the network have replicated, the double-sized network divides to form two progeny structures which are each identical to the parent network.

Original languageEnglish (US)
Pages (from-to)1064-1069
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume29
Issue number5 II
DOIs
StatePublished - 1980

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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