TY - JOUR
T1 - The reliability and validity of the subjective peripheral neuropathy screen
AU - Mcarthur, Julie H.
N1 - Funding Information:
The major findings of the study are that the SPNS is a reliable instrument as measured by Cronbach's alpha, and it possesses both construct and criterion-related validity. Pain, parasthesias, and numbness were the three symptoms that differentiated those with PSN from those without. Numbness was the symptom with the highest efficiency for correctly classifying subjects with PSN. Hand involvement does not appear to be an important differentiating factor for PSN, and based on this finding, further modifications of the instrument are recommended. Acknowledgments. This study was supported by NS26643 and RR00722. The author would like to thank Kay Carter and Denine Esposito for their invaluable help in the data collection, Dr. Thomasine Guberski and thesis committee for their support and encouragement of this project, and Drs. David Simpson and
PY - 1998
Y1 - 1998
N2 - Painful sensory neuropathy (PSN) is the most common neurological disorder associated with HIV infection and affects up to 30% of HIV-positive individuals. PSN may develop as a consequence of HIV infection or from the toxic effect of the antiretrovirals. Although several tools have been developed to screen for PSN, their validity and reliability has yet to be established among HIV-positive patients. The Subjective Peripheral Neuropathy Screen (SPNS) is a brief self-report tool that is currently being administered in the AIDS Clinical Trials Group. The objective of this study was to establish the psychometric properties of the SPNS screening tool for the correct identification of PSN in HIV-positive individuals. Specifically the goals were to determine the reliability, the validity, and the diagnostic efficiency of the SPNS in the detection of PSN. Data were abstracted on subjects enrolled in an ongoing natural history cohort. The SPNS was administered to a convenience sample of 39 HIV-positive individuals with PSN and 44 HIV-positive controls. Results showed the SPNS to be internally consistent (Cronbach's alpha = .86). SPNS score differences assessed by t-test were significantly different for individual symptoms ofparasthesias, numbness, and pain of the lower extremities, and for severity measures (the Clinical Severity Grade, and the Average Severity Score) behveen the HIV-positive groups (p < .05). Using Spearman 's rank, significant correlations were demonstrated between the neurological exam and the Clinical Severity Grade and the Average Severity Score, the neurological exam and vibratory quantitative sensory testing (QST) only, and the severity measures and vibratory QST only. Sensitivity and specificity analysis demonstrated that numbness of the lower extremities was the symptom with the highest efficiency for correctly classifying PSN. Thus, internal consistency, construct validity, and criteria?! related validity were confirmed with the SPNSfor the correct classification ofPSN in HIV-positive individuals.
AB - Painful sensory neuropathy (PSN) is the most common neurological disorder associated with HIV infection and affects up to 30% of HIV-positive individuals. PSN may develop as a consequence of HIV infection or from the toxic effect of the antiretrovirals. Although several tools have been developed to screen for PSN, their validity and reliability has yet to be established among HIV-positive patients. The Subjective Peripheral Neuropathy Screen (SPNS) is a brief self-report tool that is currently being administered in the AIDS Clinical Trials Group. The objective of this study was to establish the psychometric properties of the SPNS screening tool for the correct identification of PSN in HIV-positive individuals. Specifically the goals were to determine the reliability, the validity, and the diagnostic efficiency of the SPNS in the detection of PSN. Data were abstracted on subjects enrolled in an ongoing natural history cohort. The SPNS was administered to a convenience sample of 39 HIV-positive individuals with PSN and 44 HIV-positive controls. Results showed the SPNS to be internally consistent (Cronbach's alpha = .86). SPNS score differences assessed by t-test were significantly different for individual symptoms ofparasthesias, numbness, and pain of the lower extremities, and for severity measures (the Clinical Severity Grade, and the Average Severity Score) behveen the HIV-positive groups (p < .05). Using Spearman 's rank, significant correlations were demonstrated between the neurological exam and the Clinical Severity Grade and the Average Severity Score, the neurological exam and vibratory quantitative sensory testing (QST) only, and the severity measures and vibratory QST only. Sensitivity and specificity analysis demonstrated that numbness of the lower extremities was the symptom with the highest efficiency for correctly classifying PSN. Thus, internal consistency, construct validity, and criteria?! related validity were confirmed with the SPNSfor the correct classification ofPSN in HIV-positive individuals.
KW - Antiretrovirals
KW - HIV/AIDS
KW - Painful sensory neuropathy
KW - Subjective Peripheral Neuropathy Screen
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U2 - 10.1016/S1055-3290(98)80048-4
DO - 10.1016/S1055-3290(98)80048-4
M3 - Article
C2 - 9658364
AN - SCOPUS:0032110749
SN - 1055-3290
VL - 9
SP - 84
EP - 94
JO - Journal of the Association of Nurses in AIDS Care
JF - Journal of the Association of Nurses in AIDS Care
IS - 4
ER -