The release of chromatin template restrictions by natural polyribonucleotides

David G. Brown; Donald S. Coffey

doi:10.1016/0006-291X(71)90106-9

The release of chromatin template restrictions by natural polyribonucleotides

David G. Brown, Donald S. Coffey

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Certain natural RNAs are capable of releasing the DNA template restrictions on soluble rat liver chromatin, when assayed with an excess of exogenous DNA polymerase. A marked difference in the capacity for DNA template activation was observed among the RNAs isolated from yeast, Escherichia coli, rat liver and MS-2 and Q_β bacteriophages. The effects observed with the natural RNAs were compared with several synthetic polyribonucleotides.

Original language	English (US)
Pages (from-to)	326-333
Number of pages	8
Journal	Biochemical and Biophysical Research Communications
Volume	42
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(71)90106-9
State	Published - Jan 22 1971
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(71)90106-9

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title = "The release of chromatin template restrictions by natural polyribonucleotides",

abstract = "Certain natural RNAs are capable of releasing the DNA template restrictions on soluble rat liver chromatin, when assayed with an excess of exogenous DNA polymerase. A marked difference in the capacity for DNA template activation was observed among the RNAs isolated from yeast, Escherichia coli, rat liver and MS-2 and Qβ bacteriophages. The effects observed with the natural RNAs were compared with several synthetic polyribonucleotides.",

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AB - Certain natural RNAs are capable of releasing the DNA template restrictions on soluble rat liver chromatin, when assayed with an excess of exogenous DNA polymerase. A marked difference in the capacity for DNA template activation was observed among the RNAs isolated from yeast, Escherichia coli, rat liver and MS-2 and Qβ bacteriophages. The effects observed with the natural RNAs were compared with several synthetic polyribonucleotides.

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JO - Biochemical and Biophysical Research Communications

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The release of chromatin template restrictions by natural polyribonucleotides

Abstract

ASJC Scopus subject areas

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