The relative roles of blood cholesterol level and blood pressure level in the production of experimen tal aortic atheroma in rabbits

1. The amounts of aortic atheroma produced by feeding cholesterol for 8 weeks to male chinchilla and New Zealand white rabbits with widely varying levels of blood pressure and serum total cholesterol are compared. 2. The amount of atheroma increases with increasing blood pressure in a highly significant manner. 3. There is no correlation between the amount of aortic atheroma and the level of serum cholesterol in rabbits with the levels of blood cholesterol such as are present in this experiment.