The relationship of blood lead to systolic blood pressure in a longitudinal study of policemen

S. T. Weiss, Alvaro Munoz, A. Stein, D. Sparrow, F. E. Speizer

Research output: Contribution to journalArticle

Abstract

We examined the relationship of blood lead level to systolic and diastolic blood pressure in a longitudinal study of 89 Boston, MA, policemen. At the second examination blood level and blood pressure were measured in triplicate. Blood pressure measurements were taken in a similar fashion in years 3, 4, and 5. Multivariate analysis using a first-order autoregressive model revealed that after adjusting for previous systolic blood pressure, body mass index, age, and cigarette smoking, an elevated blood lead level was a significant predictor of subsequent systolic blood pressure. Bootstrap simulations of these models provided supporting evidence for the observed association. These data suggest that blood lead level can influence systolic blood pressure even within the normal range.

Original languageEnglish (US)
Pages (from-to)53-56
Number of pages4
JournalEnvironmental Health Perspectives
Volume78
StatePublished - 1988
Externally publishedYes

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Blood pressure
Longitudinal Studies
Blood
blood
Blood Pressure
Pressure measurement
Tobacco Products
smoking
multivariate analysis
body mass
Reference Values
Body Mass Index
Multivariate Analysis
Smoking

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health

Cite this

The relationship of blood lead to systolic blood pressure in a longitudinal study of policemen. / Weiss, S. T.; Munoz, Alvaro; Stein, A.; Sparrow, D.; Speizer, F. E.

In: Environmental Health Perspectives, Vol. 78, 1988, p. 53-56.

Research output: Contribution to journalArticle

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