TY - JOUR
T1 - The relationship of anxiety, depression, and quality of life in adults with left ventricular assist devices
AU - Casida, Jesus M.
AU - Abshire, Martha
AU - Ghosh, Bidisha
AU - Yang, James J.
N1 - Funding Information:
From the *University of Michigan School of Nursing, Ann Arbor, Michigan; and †Johns Hopkins University School of Nursing, Baltimore, Maryland. Submitted for consideration May 2017; accepted for publication in revised form August 2017. Disclosure: The authors have no conflicts of interest to report. This work was supported by the NIH, NINR, T32 NR012704 (M.A.), 1F31NR015179-01A1 (M.A.), Heart Failure Society of America Nurse Research Grant (M.A.; 2014–2016), and the Pre-doctoral Training in Research Program (NIH 5TL1TR001078-02; M.A.; 2014–2015). Correspondence: Jesus M. Casida, University of Michigan School of Nursing 426 North Ingalls, Ann Arbor, MI 48109 Copyright © 2017 by the ASAIO
Publisher Copyright:
Copyright © 2017 by the ASAIO
PY - 2018
Y1 - 2018
N2 - Psychological distress, including anxiety and depression, is commonly reported by patients with implantable left ventricular assist devices (LVADs). Still, the influence of anxiety and depression on global quality of life (QOL) is unknown. Moreover, the empirical data of LVAD patients' QOL is limited to 24 months. This study examined the differences in anxiety, depression, and QOL based on 3 LVAD implant duration groups (≤12, 13-24, and ≥25 months). We also examined the influence of anxiety and depression on QOL. An observational cross-sectional study design was employed using self-administered demographics, anxiety, depression, and global QOL questionnaires. A total of 100 patients (mean age 52 ± 13.3 years) across the United States completed the study. In the 3 implant duration groups, we found no significant differences in anxiety and depression, but the global QOL scores of patients with LVADs ≥ 13 months were significantly worse than those of patients with LVADs ≤ 12 months. Also, the correlations between QOL and either anxiety or depression were significant: Pearson's r ranged from −0.44 to −0.65 with all p values <0.0001. Compared with anxiety, depression is a stronger predictor of QOL. Our data showed that when depression is increased by 1 unit, the average QOL decreased by 0.76 units, assuming anxiety is held constant. This study uncovered relationships among anxiety, depression, and QOL in patients with long-term LVADs. Longitudinal research is needed to confirm our findings and explore factors that may contribute to worse QOL, particularly, those patients supported with LVADs beyond 13 months.
AB - Psychological distress, including anxiety and depression, is commonly reported by patients with implantable left ventricular assist devices (LVADs). Still, the influence of anxiety and depression on global quality of life (QOL) is unknown. Moreover, the empirical data of LVAD patients' QOL is limited to 24 months. This study examined the differences in anxiety, depression, and QOL based on 3 LVAD implant duration groups (≤12, 13-24, and ≥25 months). We also examined the influence of anxiety and depression on QOL. An observational cross-sectional study design was employed using self-administered demographics, anxiety, depression, and global QOL questionnaires. A total of 100 patients (mean age 52 ± 13.3 years) across the United States completed the study. In the 3 implant duration groups, we found no significant differences in anxiety and depression, but the global QOL scores of patients with LVADs ≥ 13 months were significantly worse than those of patients with LVADs ≤ 12 months. Also, the correlations between QOL and either anxiety or depression were significant: Pearson's r ranged from −0.44 to −0.65 with all p values <0.0001. Compared with anxiety, depression is a stronger predictor of QOL. Our data showed that when depression is increased by 1 unit, the average QOL decreased by 0.76 units, assuming anxiety is held constant. This study uncovered relationships among anxiety, depression, and QOL in patients with long-term LVADs. Longitudinal research is needed to confirm our findings and explore factors that may contribute to worse QOL, particularly, those patients supported with LVADs beyond 13 months.
KW - Anxiety and depression
KW - Overall quality of life
KW - Psychological distress
KW - Ventricular assist device
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U2 - 10.1097/MAT.0000000000000681
DO - 10.1097/MAT.0000000000000681
M3 - Article
C2 - 29028692
AN - SCOPUS:85056732750
SN - 1058-2916
VL - 64
SP - 515
EP - 520
JO - ASAIO Journal
JF - ASAIO Journal
IS - 4
ER -