The relationship between cotinine and periodontal disease.

Natalie M. Leow, Marie Christine Morel-Kopp, Mark Woodward, Qiang Chen, Geoffrey H. Tofler, Barbara A. Taylor

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Smoking is a risk factor for periodontitis but there are conflicting reports about the relationship between the severity of periodontitis and smoking behaviour, in part because self-reported smoking status may be inaccurate. Cotinine, a major metabolite of nicotine with a longer half-life (17 h versus 30 min), may be a more useful biochemical marker of smoking status. Smoking behaviour, plasma cotinine levels, and measures of periodontitis severity in 135 adults with moderate-advanced periodontitis were studied. Smokers had comparable periodontitis at a younger age than non-smokers. Smoking, as measured by cigarettes smoked per day and plasma cotinine levels, was significantly related to the severity of periodontitis.

Original languageEnglish (US)
Pages (from-to)51-52
Number of pages2
JournalAnnals of the Royal Australasian College of Dental Surgeons
StatePublished - Sep 2006

ASJC Scopus subject areas

  • Medicine(all)


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