The relationship between cardiac autonomic tone and T-wave morphology during ambulatory monitoring

S. D. Nelson, L. R. Dunn, B. C. Johnston, J. M. Burroughs, C. J. Love, S. F. Schaal

Research output: Contribution to journalArticle

Abstract

Intermittent T-wave inversions are known to occur during ambulatory monitoring in the absence of myocardial ischemia. The purpose of this study was to determine if T-wave inversions are associated with alterations in cardiac autonomic nervous system tone by examining the power spectrum of heart rate variability (HRV) during ambulatory monitoring. Twenty-eight episodes of T-wave inversions were analyzed from 17 youthful patients (8 men, 9 women; mean age 33.7 ± 7.3 years) who had no clinical evidence of coronary disease. Mean heart rate and total HRV (standard deviation of mean heart rate) increased during T-wave inversion from 83 ± 13 to 90 ± 13 bpm, p < 0.05, and from 56.6 ± 29.6 to 73.6 ± 36.8 ms, p < 0.015, respectively. The power spectrum of the HRV showed an increase in the low frequency components (9.28 ± 6.70 bpm2 before vs. 16.45 ± 11.63 bpm2 during T-wave inversion; p < 0.05). In contrast, the high frequency components did not change significantly during T-wave inversion (3.46 ± 3.52 bpm2 before vs. 3.53 ± 4.30 bpm2 during T-wave inversion). Three patients experienced dizziness, dyspnea or palpitations during T-wave inversion. In conclusion, T-wave inversions, recorded during ambulatory monitoring in patients with a low probability of coronary disease, are associated with an increase in the HRV which is predominantly due to augmentation of the low frequency components without significant change in the high frequency components of the power spectrum. These data suggest that augmentation in cardiac sympathetic tone may influence T-wave morphology in the absence of myocardial ischemia.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalAmerican Journal of Noninvasive Cardiology
Volume8
Issue number2
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

Keywords

  • Ambulatory monitoring
  • Cardiac autonomic tone
  • T waves

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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