The relationship between antidepressant use and smoking cessation in pregnant women in treatment for substance abuse

Margaret S. Chisolm, Emily P. Brigham, Michelle Tuten, Eric C. Strain, Hendree Evelyn Jones

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Bupropion's efficacy for smoking cessation in pregnant women is unknown. Objectives: To determine if substance-dependent women prescribed bupropion smoked fewer cigarettes/day than those prescribed citalopram/ escitalopram or no antidepressant medication. Methods: Comparison of smoking in bupropion (n 11), citalopram/escitalopram (n 17), and no antidepressant (n 28) groups. Results and Conclusions: Trend for greater decrease in smoking for the bupropion vs. citalopram/escitalopram group -6.4 vs. -.4 cigarettes/day (p .276), although the bupropion decrease was similar to that seen in the no antidepressant group -5.3 cigarettes/day. Scientific Significance: Data support continued study of bupropion in depressed pregnant substance-dependent smokers.

Original languageEnglish (US)
Pages (from-to)46-51
Number of pages6
JournalAmerican Journal of Drug and Alcohol Abuse
Volume36
Issue number1
DOIs
StatePublished - Feb 19 2010

Keywords

  • Addiction
  • Antidepressants
  • Pregnancy
  • Smoking
  • Substance abuse

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health

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