Arthritis occurred in 20 (30 per cent) of 67 patients with nongranulomatous uveitis, but in only 8 (3 per cent) of 277 patients with other uveal lesions. It was more common in patients wth recurrent, acute rather than persistent, chronic nongranulomatous uveitis. The arthritis had distinctive features. It was usually an asymmetrical, nonankylosing, peripheral polyarthritis involving the lower extremities more frequently than the upper ones. In addition, ankylosing spondylitis was present in almost all male but in no female arthritis patients. Rheumatoid factor could not be demonstrated in the sera of these patients. The data suggest a relation between nongranulomatous uveitis and a distinctive type of arthritis.
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