The rational design of an AIDS vaccine

Daniel C. Douek, Peter D. Kwong, Gary J. Nabel

Research output: Contribution to journalArticle


The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development. AIDS vaccine design requires a scientifically driven, rational approach that encompasses the latest advances in viral molecular genetics, structural biology, and immunology.

Original languageEnglish (US)
Pages (from-to)677-681
Number of pages5
Issue number4
Publication statusPublished - Feb 24 2006
Externally publishedYes


ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Douek, D. C., Kwong, P. D., & Nabel, G. J. (2006). The rational design of an AIDS vaccine. Cell, 124(4), 677-681.