The quantitative accuracy and efficiency of the dual reconstruction scheme including a practical scatter/random approximation in dynamic PET imaging

Ju Chieh Cheng, Arman Rahmim, Stephan Blinder, Katherine Dinelle, Vesna Sossi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe a time-efficient reconstruction scheme with a practical approximate scatter and random correction for dynamic PET imaging on scanners with large data sets such as the High Resolution Research Tomograph (HRRT). This dual (histogram/list-mode) reconstruction scheme makes use of the efficiency advantage of both histogram and list-mode reconstructions (i.e. histogram-mode reconstruction is applied to the dynamic frames with a large number of counts, and list-mode reconstruction is applied to the frames with a low number of counts). The practical scatter and random approximation technique is based on a time averaged scatter and random estimate followed by scaling according to the global numbers of true and random events for each temporal frame. The quantitative accuracy of this dual reconstruction scheme including the scatter and random approximation was examined by comparing the time activity curves (TAC) obtained from the images reconstructed using the conventional histogram-mode algorithm and those obtained from applying the dual reconstruction scheme with the practical approximation. A representative dynamic 11C non-human primate study with 14 temporal frames is presented here, and an excellent agreement between the conventional and the proposed scheme was found, while an overall gain of about 35% in time (which depends on the number of dynamic frames; the more frames with a similar spatial activity distribution there are, the more time we gain) and an over 4 times less storage cost for the scatter and random data sets (sinograms) was achieved in this case.

Original languageEnglish (US)
Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2744-2747
Number of pages4
ISBN (Print)1424405610, 9781424405619
DOIs
StatePublished - Jan 1 2006
Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
Duration: Oct 29 2006Nov 4 2006

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume5
ISSN (Print)1095-7863

Other

Other2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
CountryUnited States
CitySan Diego, CA
Period10/29/0611/4/06

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ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Cheng, J. C., Rahmim, A., Blinder, S., Dinelle, K., & Sossi, V. (2006). The quantitative accuracy and efficiency of the dual reconstruction scheme including a practical scatter/random approximation in dynamic PET imaging. In 2006 IEEE Nuclear Science Symposium - Conference Record (pp. 2744-2747). [4179604] (IEEE Nuclear Science Symposium Conference Record; Vol. 5). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2006.356447