TY - JOUR
T1 - The Promise of Metastasis-Directed Therapy for Oligometastatic Prostate Cancer
T2 - Going Beneath the Surface with Molecular Imaging
AU - Sutera, Philip
AU - Phillips, Ryan M.
AU - Deek, Matthew
AU - Ozyigit, Gokhan
AU - Onal, Cem
AU - Tran, Phuoc T.
N1 - Funding Information:
Phuoc Tran was funded by an anonymous donor, the Movember Foundation–Distinguished Gentlemen’s Ride–Prostate Cancer Foundation, Barbara’s Fund, the National Capitol Cancer Research Fund, the NIH/NCI (U01CA212007 and U01CA231776), and the DoD (W81XWH-21-1-0296). No other potential conflict of interest relevant to this article was reported.
Publisher Copyright:
© 2022 by the Society of Nuclear Medicine and Molecular Imaging.
PY - 2022/3/1
Y1 - 2022/3/1
N2 - Historically, metastatic disease was thought to represent an all-or-nothing incurable state, distinct from curable localized disease and necessitating treatment with systemic therapy alone. The role for life-prolonging local therapy was known to be futile. This dogma was challenged in the 1990s with the reframing of metastasis as a spectrum rather than binary, resulting in the postulation of a low-volume metastatic state, given the term oligometastasis, which may actually be curable with definitive local therapy.
AB - Historically, metastatic disease was thought to represent an all-or-nothing incurable state, distinct from curable localized disease and necessitating treatment with systemic therapy alone. The role for life-prolonging local therapy was known to be futile. This dogma was challenged in the 1990s with the reframing of metastasis as a spectrum rather than binary, resulting in the postulation of a low-volume metastatic state, given the term oligometastasis, which may actually be curable with definitive local therapy.
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U2 - 10.2967/JNUMED.121.263684
DO - 10.2967/JNUMED.121.263684
M3 - Article
C2 - 35058322
AN - SCOPUS:85125554388
SN - 0161-5505
VL - 63
SP - 339
EP - 341
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
IS - 3
ER -