The prevalence of long QT interval in post-operative intensive care unit patients

Research output: Contribution to journalArticle

Abstract

The severity of patient illnesses and medication complexity in post-operative critically ill patients increase the risk for a prolonged QT interval. We determined the prevalence of prolonged QTc in surgical intensive care unit (SICU) patients. We performed a prospective cross-sectional study over a 15-month period at a major academic center. SICU pre-admission and admission EKGs, patient demographics, and laboratory values were analyzed. QTc was evaluated as both a continuous and dichotomous outcome (prolonged QTc > 440 ms). 281 patients were included in the study: 92 % (n = 257) post-operative and 8 % (n = 24) non-operative. On pre-admission EKGs, 32 % of the post-operative group and 42 % of the non-operative group had prolonged QTc (p = 0.25); on post-admission EKGs, 67 % of the post-operative group but only 33 % of the non-operative group had prolonged QTc (p 

Original languageEnglish (US)
Pages (from-to)437-443
Number of pages7
JournalJournal of Clinical Monitoring and Computing
Volume30
Issue number4
DOIs
StatePublished - Aug 1 2016

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Intensive Care Units
Electrocardiography
Critical Care
Patient Admission
Critical Illness
Cross-Sectional Studies
Demography

Keywords

  • Arrhythmia
  • Long QT
  • Post-operative
  • Surgical intensive care unit
  • Torsades de pointes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Critical Care and Intensive Care Medicine
  • Health Informatics

Cite this

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title = "The prevalence of long QT interval in post-operative intensive care unit patients",
abstract = "The severity of patient illnesses and medication complexity in post-operative critically ill patients increase the risk for a prolonged QT interval. We determined the prevalence of prolonged QTc in surgical intensive care unit (SICU) patients. We performed a prospective cross-sectional study over a 15-month period at a major academic center. SICU pre-admission and admission EKGs, patient demographics, and laboratory values were analyzed. QTc was evaluated as both a continuous and dichotomous outcome (prolonged QTc > 440 ms). 281 patients were included in the study: 92 {\%} (n = 257) post-operative and 8 {\%} (n = 24) non-operative. On pre-admission EKGs, 32 {\%} of the post-operative group and 42 {\%} of the non-operative group had prolonged QTc (p = 0.25); on post-admission EKGs, 67 {\%} of the post-operative group but only 33 {\%} of the non-operative group had prolonged QTc (p ",
keywords = "Arrhythmia, Long QT, Post-operative, Surgical intensive care unit, Torsades de pointes",
author = "Pham, {Julius Cuong} and Banks, {Michael C} and Narotsky, {David L.} and Todd Dorman and Winters, {Bradford D}",
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AU - Dorman, Todd

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N2 - The severity of patient illnesses and medication complexity in post-operative critically ill patients increase the risk for a prolonged QT interval. We determined the prevalence of prolonged QTc in surgical intensive care unit (SICU) patients. We performed a prospective cross-sectional study over a 15-month period at a major academic center. SICU pre-admission and admission EKGs, patient demographics, and laboratory values were analyzed. QTc was evaluated as both a continuous and dichotomous outcome (prolonged QTc > 440 ms). 281 patients were included in the study: 92 % (n = 257) post-operative and 8 % (n = 24) non-operative. On pre-admission EKGs, 32 % of the post-operative group and 42 % of the non-operative group had prolonged QTc (p = 0.25); on post-admission EKGs, 67 % of the post-operative group but only 33 % of the non-operative group had prolonged QTc (p 

AB - The severity of patient illnesses and medication complexity in post-operative critically ill patients increase the risk for a prolonged QT interval. We determined the prevalence of prolonged QTc in surgical intensive care unit (SICU) patients. We performed a prospective cross-sectional study over a 15-month period at a major academic center. SICU pre-admission and admission EKGs, patient demographics, and laboratory values were analyzed. QTc was evaluated as both a continuous and dichotomous outcome (prolonged QTc > 440 ms). 281 patients were included in the study: 92 % (n = 257) post-operative and 8 % (n = 24) non-operative. On pre-admission EKGs, 32 % of the post-operative group and 42 % of the non-operative group had prolonged QTc (p = 0.25); on post-admission EKGs, 67 % of the post-operative group but only 33 % of the non-operative group had prolonged QTc (p 

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