Abstract
The study examined 75 autistic individuals who met DSM-III-R criteria for autistic disorder at 5 years of age. Diagnosis was based on information elicited using a standardized interview for autism. Two of 75 (2.7%) autistic subjects expressed the fragile X marker (Xq27.3) in 40% of cells counted and had other affected family members. Two additional subjects expressed the fragile X anomaly at low rates (1%). These rates are compared with those reported in other studies. Methodological differences, which may underlie the varying rates reported across studies, are discussed.
Original language | English (US) |
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Pages (from-to) | 825-830 |
Number of pages | 6 |
Journal | Journal of the American Academy of Child and Adolescent Psychiatry |
Volume | 30 |
Issue number | 5 |
DOIs | |
State | Published - 1991 |
Externally published | Yes |
Keywords
- autism
- fragile X
- structured interview
ASJC Scopus subject areas
- Developmental and Educational Psychology
- Psychiatry and Mental health