The power ratio and the interval map

Spiking models and extracellular recordings

Daniel S. Reich, Jonathan D. Victor, Bruce W. Knight

Research output: Contribution to journalArticle

Abstract

We describe a new, computationally simple method for analyzing the dynamics of neuronal spike trains driven by external stimuli. The goal of our method is to test the predictions of simple spike-generating models against extracellularly recorded neuronal responses. Through a new statistic called the power ratio, we distinguish between two broad classes of responses: (1) responses that can be completely characterized by a variable firing rate, (for example, modulated Poisson and gamma spike trains); and (2) responses for which firing rate variations alone are not sufficient to characterize response dynamics (for example, leaky integrate-and-fire spike trains as well as Poisson spike trains with long absolute refractory periods). We show that the responses of many visual neurons in the cat retinal ganglion, cat lateral geniculate nucleus, and macaque primary visual cortex fall into the second class, which implies that the pattern of spike times can carry significant information about visual stimuli. Our results also suggest that spike trains of X-type retinal ganglion cells, in particular are very similar to spike trains generated by a leaky integrate-and-fire model with additive, stimulus- independent, noise that could represent background synaptic activity.

Original languageEnglish (US)
Pages (from-to)10090-10104
Number of pages15
JournalJournal of Neuroscience
Volume18
Issue number23
StatePublished - Dec 1 1998
Externally publishedYes

Fingerprint

Cats
Geniculate Bodies
Retinal Ganglion Cells
Macaca
Visual Cortex
Ganglia
Noise
Neurons

Keywords

  • Integrate-and-fire
  • Interval distributions
  • Lateral geniculate nucleus
  • Neural models
  • Neural noise
  • Poisson process
  • Primary visual cortex
  • Rate coding
  • Refractory period
  • Renewal process
  • Retinal ganglion
  • Spike trains
  • Temporal coding

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Reich, D. S., Victor, J. D., & Knight, B. W. (1998). The power ratio and the interval map: Spiking models and extracellular recordings. Journal of Neuroscience, 18(23), 10090-10104.

The power ratio and the interval map : Spiking models and extracellular recordings. / Reich, Daniel S.; Victor, Jonathan D.; Knight, Bruce W.

In: Journal of Neuroscience, Vol. 18, No. 23, 01.12.1998, p. 10090-10104.

Research output: Contribution to journalArticle

Reich, DS, Victor, JD & Knight, BW 1998, 'The power ratio and the interval map: Spiking models and extracellular recordings', Journal of Neuroscience, vol. 18, no. 23, pp. 10090-10104.
Reich, Daniel S. ; Victor, Jonathan D. ; Knight, Bruce W. / The power ratio and the interval map : Spiking models and extracellular recordings. In: Journal of Neuroscience. 1998 ; Vol. 18, No. 23. pp. 10090-10104.
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