The potential relevance of growth hormone to female reproductive physiology and pathophysiology

E. Katz; E. Ricciarelli; E. Y. Adashi

doi:10.1016/S0015-0282(16)55610-6

The potential relevance of growth hormone to female reproductive physiology and pathophysiology

E. Katz, E. Ricciarelli, E. Y. Adashi

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

Objective: To assess possible interfacing between the somatotrophic and reproductive axes. Design: Literature review. Main Outcome Measures: Ovarian growth hormone reception and action. Results: The available literature strongly supports a permissive role for the somatotrophic axis in the reproductive process. Conclusions: Although a role for growth hormone in reproductive biology appears highly likely, its relevance to the process of puberty and to the normal workings of the menstrual cycle, as well as its possible application in reproductive pathology must await further investigation.

Original language	English (US)
Pages (from-to)	8-34
Number of pages	27
Journal	Fertility and sterility
Volume	59
Issue number	1
DOIs	https://doi.org/10.1016/S0015-0282(16)55610-6
State	Published - 1993
Externally published	Yes

Keywords

Growth hormone
insulin-like growth factor I
ovary
ovulation induction
reproduction

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/S0015-0282(16)55610-6

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AU - Ricciarelli, E.

AU - Adashi, E. Y.

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AB - Objective: To assess possible interfacing between the somatotrophic and reproductive axes. Design: Literature review. Main Outcome Measures: Ovarian growth hormone reception and action. Results: The available literature strongly supports a permissive role for the somatotrophic axis in the reproductive process. Conclusions: Although a role for growth hormone in reproductive biology appears highly likely, its relevance to the process of puberty and to the normal workings of the menstrual cycle, as well as its possible application in reproductive pathology must await further investigation.

KW - Growth hormone

KW - insulin-like growth factor I

KW - ovary

KW - ovulation induction

KW - reproduction

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The potential relevance of growth hormone to female reproductive physiology and pathophysiology

Abstract

Keywords

ASJC Scopus subject areas

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