The potential of molecular screening

S. A. Ahrendt, D. Sidransky

Research output: Contribution to journalReview articlepeer-review


Impressive results have been reported for several molecular screening tests for a number of human cancers and clearly demonstrate the potential of these assays at detecting cancer. However, before the introduction of these assays into clinical use, further studies are clearly needed. A prospective comparison between conventional screening methods and the newer molecular techniques documenting improved detection rates in patients with early stage cancers is required before these assays are adapted into clinical practice. In addition, broad technical improvements in molecular detection assays and high throughput automation are necessary for eventual clinical implementation. In the not-too-distant future, surgeons may be called on to identify and eradicate clinically occult disease in patients with a positive molecular screen.

Original languageEnglish (US)
Pages (from-to)641-656
Number of pages16
JournalSurgical Oncology Clinics of North America
Issue number4
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Oncology


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