The potential economic value of a hookworm vaccine

Bruce Y. Lee, Kristina M. Bacon, Rachel Bailey, Ann E. Wiringa, Kenneth J. Smith

Research output: Contribution to journalArticle

Abstract

Hookworm infection is a significant problem worldwide. As development of hookworm vaccine proceeds, it is essential for vaccine developers and manufacturers, policy makers, and other public health officials to understand the potential costs and benefits of such a vaccine. We developed a decision analytic model to evaluate the cost-effectiveness of introducing a hookworm vaccine into two populations in Brazil: school-age children and non-pregnant women of reproductive age. Results suggest that a vaccine would provide not only cost savings, but potential health benefits to both populations. In fact, the most cost-effective intervention strategy may be to combine vaccine with current drug treatment strategies.

Original languageEnglish (US)
Pages (from-to)1201-1210
Number of pages10
JournalVaccine
Volume29
Issue number6
DOIs
StatePublished - Feb 1 2011
Externally publishedYes

Keywords

  • Computer simulation
  • Economics
  • Hookworm vaccine

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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  • Cite this

    Lee, B. Y., Bacon, K. M., Bailey, R., Wiringa, A. E., & Smith, K. J. (2011). The potential economic value of a hookworm vaccine. Vaccine, 29(6), 1201-1210. https://doi.org/10.1016/j.vaccine.2010.12.004