The physiological connection: Stimulating the human and amphibian retina

Gislin Dagnelie, Mark Humayun, Robert Greenberg, Eugene De Juan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To explore the feasibility of an intraocular visual prosthesis for the restoration of sight in blind individuals the authors have performed electrical stimulation experiments in alert human subjects and in amphibian retina preparations. Subjects were legally blind from retinitis pigmentosa or age-related macular degeneration, in whom a substantial fraction of inner retinal cells is thought to remain functional. Data from 11 subjects are presented. All experienced localized visual percepts, and resolution if tested, was on the order of 1 to 2, suggesting the feasibility of at least ambulatory vision. Data from both human and animal subjects indicate that more than one cell type can be stimulated, and that selective stimulation of a particular cell type may be possible. The authors argue that a straightforward image processing and stimulus delivery system may suffice for the production of pixelized prosthetic vision, and that supervised learning of the human recipient will be more important than that of the prosthesis.

Original languageEnglish (US)
Title of host publication1997 IEEE International Conference on Neural Networks, ICNN 1997
Pages2321-2326
Number of pages6
DOIs
StatePublished - Dec 1 1997
Event1997 IEEE International Conference on Neural Networks, ICNN 1997 - Houston, TX, United States
Duration: Jun 9 1997Jun 12 1997

Publication series

NameIEEE International Conference on Neural Networks - Conference Proceedings
Volume4
ISSN (Print)1098-7576

Conference

Conference1997 IEEE International Conference on Neural Networks, ICNN 1997
CountryUnited States
CityHouston, TX
Period6/9/976/12/97

ASJC Scopus subject areas

  • Software

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