The peptide molecular links between the central nervous and the immune systems

I. Z. Siemion; A. Kluczyk; M. Cebrat

doi:10.1007/s00726-005-0231-8

The peptide molecular links between the central nervous and the immune systems

I. Z. Siemion, A. Kluczyk, M. Cebrat

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The central nervous system (CNS) and the immune system were for many years considered as two autonomous systems. Now, the reciprocal connections between them are generally recognized and very well documented. The links are realized mainly by various immuno- and neuropeptides. In the review the influence of the following immunopeptides on CNS is presented: tuftsin, thymulin, thymopoietin and thymopentin, thymosins, and thymic humoral factor. On the other side, the activity in the immune system of such neuropeptides as substance P, neurotensin, some neurokinins, enkephalins, and endorphins is discussed.

Original language	English (US)
Pages (from-to)	161-176
Number of pages	16
Journal	Amino Acids
Volume	29
Issue number	3
DOIs	https://doi.org/10.1007/s00726-005-0231-8
State	Published - Nov 2005
Externally published	Yes

Keywords

CNS-immune system molecular links
Immunopeptides
Neuropeptides
Thymic peptides

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry
Endocrinology

Access to Document

10.1007/s00726-005-0231-8

Cite this

@article{66e15a3e2b744b0ca3270effffb0bb13,

title = "The peptide molecular links between the central nervous and the immune systems",

abstract = "The central nervous system (CNS) and the immune system were for many years considered as two autonomous systems. Now, the reciprocal connections between them are generally recognized and very well documented. The links are realized mainly by various immuno- and neuropeptides. In the review the influence of the following immunopeptides on CNS is presented: tuftsin, thymulin, thymopoietin and thymopentin, thymosins, and thymic humoral factor. On the other side, the activity in the immune system of such neuropeptides as substance P, neurotensin, some neurokinins, enkephalins, and endorphins is discussed.",

keywords = "CNS-immune system molecular links, Immunopeptides, Neuropeptides, Thymic peptides",

author = "Siemion, {I. Z.} and A. Kluczyk and M. Cebrat",

year = "2005",

month = nov,

doi = "10.1007/s00726-005-0231-8",

language = "English (US)",

volume = "29",

pages = "161--176",

journal = "Amino Acids",

issn = "0939-4451",

publisher = "Springer Wien",

number = "3",

}

TY - JOUR

T1 - The peptide molecular links between the central nervous and the immune systems

AU - Siemion, I. Z.

AU - Kluczyk, A.

AU - Cebrat, M.

PY - 2005/11

Y1 - 2005/11

N2 - The central nervous system (CNS) and the immune system were for many years considered as two autonomous systems. Now, the reciprocal connections between them are generally recognized and very well documented. The links are realized mainly by various immuno- and neuropeptides. In the review the influence of the following immunopeptides on CNS is presented: tuftsin, thymulin, thymopoietin and thymopentin, thymosins, and thymic humoral factor. On the other side, the activity in the immune system of such neuropeptides as substance P, neurotensin, some neurokinins, enkephalins, and endorphins is discussed.

AB - The central nervous system (CNS) and the immune system were for many years considered as two autonomous systems. Now, the reciprocal connections between them are generally recognized and very well documented. The links are realized mainly by various immuno- and neuropeptides. In the review the influence of the following immunopeptides on CNS is presented: tuftsin, thymulin, thymopoietin and thymopentin, thymosins, and thymic humoral factor. On the other side, the activity in the immune system of such neuropeptides as substance P, neurotensin, some neurokinins, enkephalins, and endorphins is discussed.

KW - CNS-immune system molecular links

KW - Immunopeptides

KW - Neuropeptides

KW - Thymic peptides

UR - http://www.scopus.com/inward/record.url?scp=28644445410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=28644445410&partnerID=8YFLogxK

U2 - 10.1007/s00726-005-0231-8

DO - 10.1007/s00726-005-0231-8

M3 - Article

C2 - 16059661

AN - SCOPUS:28644445410

SN - 0939-4451

VL - 29

SP - 161

EP - 176

JO - Amino Acids

JF - Amino Acids

IS - 3

ER -

The peptide molecular links between the central nervous and the immune systems

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this