The pattern of vertebral involvement in metastatic vertebral breast cancer

P. L. Asdourian, M. Weidenbaum, R. L. DeWald, K. W. Hammerberg, R. G. Ramsey

Research output: Contribution to journalArticle


The spine is a common site of bony metastasis. To date, studies have not identified the initial site and pattern of vertebral metastasis in a homogeneous group of patients. Twenty-seven magnetic resonance imaging studies performed on 25 patients with metastatic vertebral breast cancer were reviewed retrospectively. The location and extent of metastatic vertebral involvement were determined. The vertebral body is the most frequent initial site of metastatic seeding. Although radiographically an absent pedicle is often the first sign of metastatic disease, involvement of the pedicle is by direct extension from either the vertebral body or the posterior elements and is therefore a late occurrence in the disease process.

Original languageEnglish (US)
Pages (from-to)164-170
Number of pages7
JournalClinical Orthopaedics and Related Research
Issue number250
Publication statusPublished - 1990
Externally publishedYes


ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Asdourian, P. L., Weidenbaum, M., DeWald, R. L., Hammerberg, K. W., & Ramsey, R. G. (1990). The pattern of vertebral involvement in metastatic vertebral breast cancer. Clinical Orthopaedics and Related Research, (250), 164-170.