TY - JOUR
T1 - The pattern of proton magnetic resonance spectroscopy in non-neoplastic encephalic lesions
AU - Faria, Andréia V.
AU - Reis, Fabiano
AU - Zanardi, Verônica A.
AU - Menezes, José R.
AU - Cendes, Fernando
PY - 2004/6
Y1 - 2004/6
N2 - The purpose of this article is show the role of proton magnetic resonance spectroscopy (MRS), associated with magnetic resonance images, in the study of non-neoplastic disorders, helping in diagnosis and better characterization of the nature of the lesion. Herein, we analyzed single voxel proton spectroscopy in eight different non-neoplastic lesions, displayed in six categories (infectious, ischaemic, demyelinating, inflammatory, malformation of development and phacomatosis). The presence or the ratios of signal intensities brain tissue metabolites observed with this technique (N-acetyl aspartate, choline, creatine, lactate and lipids) helped in their differentiation with neoplastic lesions and helped in correct diagnosis. In infectious diseases, signals of acetate, succinate and aminoacids were also important. In conclusion, proton MRS is a noninvasive method, very useful as an additional technique to define the nature of non-neoplastic encephalic lesions.
AB - The purpose of this article is show the role of proton magnetic resonance spectroscopy (MRS), associated with magnetic resonance images, in the study of non-neoplastic disorders, helping in diagnosis and better characterization of the nature of the lesion. Herein, we analyzed single voxel proton spectroscopy in eight different non-neoplastic lesions, displayed in six categories (infectious, ischaemic, demyelinating, inflammatory, malformation of development and phacomatosis). The presence or the ratios of signal intensities brain tissue metabolites observed with this technique (N-acetyl aspartate, choline, creatine, lactate and lipids) helped in their differentiation with neoplastic lesions and helped in correct diagnosis. In infectious diseases, signals of acetate, succinate and aminoacids were also important. In conclusion, proton MRS is a noninvasive method, very useful as an additional technique to define the nature of non-neoplastic encephalic lesions.
KW - Magnetic resonance
KW - Non-neoplastic encephalic lesions
KW - Spectroscopy
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U2 - 10.1590/S0004-282X2004000300010
DO - 10.1590/S0004-282X2004000300010
M3 - Article
C2 - 15273839
AN - SCOPUS:3142752236
SN - 0004-282X
VL - 62
SP - 429
EP - 436
JO - Arquivos de Neuro-Psiquiatria
JF - Arquivos de Neuro-Psiquiatria
IS - 2 B
ER -