The pattern of proton magnetic resonance spectroscopy in non-neoplastic encephalic lesions

Andréia V. Faria, Fabiano Reis, Verônica A. Zanardi, José R. Menezes, Fernando Cendes

Research output: Contribution to journalArticle

Abstract

The purpose of this article is show the role of proton magnetic resonance spectroscopy (MRS), associated with magnetic resonance images, in the study of non-neoplastic disorders, helping in diagnosis and better characterization of the nature of the lesion. Herein, we analyzed single voxel proton spectroscopy in eight different non-neoplastic lesions, displayed in six categories (infectious, ischaemic, demyelinating, inflammatory, malformation of development and phacomatosis). The presence or the ratios of signal intensities brain tissue metabolites observed with this technique (N-acetyl aspartate, choline, creatine, lactate and lipids) helped in their differentiation with neoplastic lesions and helped in correct diagnosis. In infectious diseases, signals of acetate, succinate and aminoacids were also important. In conclusion, proton MRS is a noninvasive method, very useful as an additional technique to define the nature of non-neoplastic encephalic lesions.

Original languageEnglish (US)
Pages (from-to)429-436
Number of pages8
JournalArquivos de Neuro-Psiquiatria
Volume62
Issue number2 B
DOIs
StatePublished - Jun 2004

Keywords

  • Magnetic resonance
  • Non-neoplastic encephalic lesions
  • Spectroscopy

ASJC Scopus subject areas

  • Clinical Neurology
  • Biological Psychiatry

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