The paired availability design: A proposal for evaluating epidural analgesia during labor

Stuart G. Baker, Karen S. Lindeman

Research output: Contribution to journalArticlepeer-review

Abstract

The paired availability design (PAD) can reduce selection bias when it is not possible to randomize subjects. PAD consists of independent pairs of experimental and control groups. Within each pair, the intervention is the availability of treatment not its receipt. In the experimental group, the new treatment is made available to all subjects although some may not receive it. In the control group, the experimental treatment is generally not available to subjects although some may receive it in special circumstances. We present a statistic to test a null hypothesis that the receipt of intervention will increase response by a specified non‐zero amount δ. We propose this design for use in a study of the effect of epidural analgesia on the rate of Caesarean section.

Original languageEnglish (US)
Pages (from-to)2269-2278
Number of pages10
JournalStatistics in Medicine
Volume13
Issue number21
DOIs
StatePublished - Nov 15 1994

ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability

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