TY - JOUR
T1 - The oxygen Bohr effect of human fetal hemoglobin
AU - Antonini, Eraldo
AU - Wyman, Jeffries
AU - Brunori, Maurizio
AU - Fronticelli, Clara
AU - Bucci, Enrico
AU - Reichlin, Morris
AU - Fanelli, Alessandro Rossi
PY - 1964/12
Y1 - 1964/12
N2 - The oxygen Bohr effect of human fetal hemoglobin has been studied both in terms of oxygen equilibrium at constant pH and of differential titrations. Fetal and adult hemoglobins have the same normal but different reverse Bohr effects, the reverse effect in fetal hemoglobin being only about half that of adult hemoglobin. The heme-heme interactions are the same for the two proteins, the value of n being equal to 2.9 ± 0.2 over the entire pH range examined.
AB - The oxygen Bohr effect of human fetal hemoglobin has been studied both in terms of oxygen equilibrium at constant pH and of differential titrations. Fetal and adult hemoglobins have the same normal but different reverse Bohr effects, the reverse effect in fetal hemoglobin being only about half that of adult hemoglobin. The heme-heme interactions are the same for the two proteins, the value of n being equal to 2.9 ± 0.2 over the entire pH range examined.
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U2 - 10.1016/0003-9861(64)90443-6
DO - 10.1016/0003-9861(64)90443-6
M3 - Article
C2 - 14244701
AN - SCOPUS:0006120777
VL - 108
SP - 569
EP - 572
JO - Archives of Biochemistry and Biophysics
JF - Archives of Biochemistry and Biophysics
SN - 0003-9861
IS - 3
ER -