@article{d94738da603048188411d1a2288fb028,
title = "The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans",
abstract = "The origin of virulence in environmental fungi that have no requirement for animal hosts in their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with virulence factors for mammalian pathogenesis that also contribute to environmental survival. C. neoformans virulence may originate from selection pressures imposed by environmental predators.",
keywords = "Amoebae, Cryptococcus neoformans, Ecology, Environment, Fungal, Fungi, Pathogenicity, Virulence, Virulence factor",
author = "Steenbergen, {Judith N.} and Arturo Casadevall",
note = "Funding Information: We are grateful to Dr. J.D. Nosanchuk for his critical reading of the review. Also, we would like to thank O. Zaragoza for providing us with the micrograph of C. neoformans with India ink depicting the capsule. J.N. Steenbergen is supported by National Institutes of Health Training Grant T32GM 07491 and A. Casadevall is supported by National Institutes of Health Awards AI33774, AI13342, and HL59842. This work is from a thesis to be submitted by J.N. Steenbergen in partial fulfillment of the requirements for the degree of doctor of philosophy in the Sue Golding Graduate Division of Medical Sciences, Albert Einstein College of Medicine, Bronx, NY.",
year = "2003",
month = jun,
doi = "10.1016/S1286-4579(03)00092-3",
language = "English (US)",
volume = "5",
pages = "667--675",
journal = "Microbes and Infection",
issn = "1286-4579",
publisher = "Elsevier Masson SAS",
number = "7",
}