The Ontario Neurodegenerative Disease Research Initiative (ONDRI)

Sali M.K. Farhan, Robert Bartha, Sandra E. Black, Dale Corbett, Elizabeth Finger, Morris Freedman, Barry Greenberg, David A. Grimes, Robert A. Hegele, Chris Hudson, Peter W. Kleinstiver, Anthony E. Lang, Mario Masellis, William E. McIlroy, Paula M. McLaughlin, Manuel Montero-Odasso, David G. Munoz, Douglas P. Munoz, Stephen Strother, Richard H. SwartzSean Symons, Maria Carmela Tartaglia, Lorne Zinman, Michael J. Strong

Research output: Contribution to journalArticle

Abstract

Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.

Original languageEnglish (US)
Pages (from-to)196-202
Number of pages7
JournalCanadian Journal of Neurological Sciences
Volume44
Issue number2
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

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Keywords

  • Alzheimer's
  • Amyotrophic Lateral Sclerosis
  • Dementia
  • Frontotemporal Dementia
  • Neurodegeneration
  • Parkinson Disease
  • vascular cognitive impairment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Farhan, S. M. K., Bartha, R., Black, S. E., Corbett, D., Finger, E., Freedman, M., Greenberg, B., Grimes, D. A., Hegele, R. A., Hudson, C., Kleinstiver, P. W., Lang, A. E., Masellis, M., McIlroy, W. E., McLaughlin, P. M., Montero-Odasso, M., Munoz, D. G., Munoz, D. P., Strother, S., ... Strong, M. J. (2017). The Ontario Neurodegenerative Disease Research Initiative (ONDRI). Canadian Journal of Neurological Sciences, 44(2), 196-202. https://doi.org/10.1017/cjn.2016.415