TY - JOUR
T1 - The Ontario Neurodegenerative Disease Research Initiative (ONDRI)
AU - Farhan, Sali M.K.
AU - Bartha, Robert
AU - Black, Sandra E.
AU - Corbett, Dale
AU - Finger, Elizabeth
AU - Freedman, Morris
AU - Greenberg, Barry
AU - Grimes, David A.
AU - Hegele, Robert A.
AU - Hudson, Chris
AU - Kleinstiver, Peter W.
AU - Lang, Anthony E.
AU - Masellis, Mario
AU - McIlroy, William E.
AU - McLaughlin, Paula M.
AU - Montero-Odasso, Manuel
AU - Munoz, David G.
AU - Munoz, Douglas P.
AU - Strother, Stephen
AU - Swartz, Richard H.
AU - Symons, Sean
AU - Tartaglia, Maria Carmela
AU - Zinman, Lorne
AU - Strong, Michael J.
N1 - Publisher Copyright:
Copyright © The Canadian Journal of Neurological Sciences Inc. 2016Â This is an open access article, distributed under the terms of the creative commons attribution licence.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.
AB - Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.
KW - Alzheimer's
KW - Amyotrophic Lateral Sclerosis
KW - Dementia
KW - Frontotemporal Dementia
KW - Neurodegeneration
KW - Parkinson Disease
KW - vascular cognitive impairment
UR - http://www.scopus.com/inward/record.url?scp=85013667366&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85013667366&partnerID=8YFLogxK
U2 - 10.1017/cjn.2016.415
DO - 10.1017/cjn.2016.415
M3 - Article
C2 - 28003035
AN - SCOPUS:85013667366
SN - 0317-1671
VL - 44
SP - 196
EP - 202
JO - Canadian Journal of Neurological Sciences
JF - Canadian Journal of Neurological Sciences
IS - 2
ER -