The nature of retinoblastoma. II. Photoreceptor differentiation: An electron microscopic study

Mark O.M. Ts'o, Ben S. Fine, Lorenz E. Zimmerman

Research output: Contribution to journalArticle

Abstract

In our histopathologic studyof retinoblastomas exhibiting an unusual form of differentiation, it seemed apparent that these tumors were producing structures resembling elements of the photoreceptor cell. An electron microscopic study was made to further detail the cytologic characteristics of these tumorcells. The cytologic similarities and differences between these differentiated tumor cells and the mature and developing normal photoreceptor cells were of special interest for investigation. Evidence of neuroglial differentiation such as formation of Müller's cells was also sought.

Original languageEnglish (US)
Pages (from-to)350-359
Number of pages10
JournalAmerican journal of ophthalmology
Volume69
Issue number3
DOIs
StatePublished - Mar 1970
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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