The natural history of prostatism: The effects of non-response bias

Laurel A. Panser, Christopher G. Chute, Harry A. Guess, Jeffrey J. Larsonkeller, Cynthia J. Girman, Joseph E. Oesterling, Michael M. Lieber, Steven J. Jacobsen, Steven J. Jacobsen

Research output: Contribution to journalArticlepeer-review

Abstract

Panser L A (Section of Clinical Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA), Chute C G, Guess H A, LarsonKeller J J, Girman C J, Oesterling J E, Lieber M M and Jacobsen S J. The natural history of prostatism: The effects of non-response bias. International Journal of Epidemiology 1994; 23: 1198-1205. Background. In epidemiological studies, non-response may raise the question of generalizabllity to the target population. Most investigations have not been able to access data that could provide information about the potential impact of non-response bias. Methods. A 55% response rate was realized at baseline for a prospective cohort investigation of the natural history of benign prostatic hyperplasia in Olmsted County, Minnesota, during 1989-1991 (the Olmsted County Study of Urinary Symptoms and Health Status Among Men). This prompted a preliminary study of potential non-response bias among full participants, partial participants and complete non-responders. The medical diagnostic index maintained by the Rochester Epidemiology Project was used to ascertain the prevalence of specific conditions in the 9 years prior to study inception. Results. The age-adjusted period prevalence rate for benign prostatic hyperplasia (%) was 9.6 (95% confidence interval [Cl]: 8.1-11.0) for full participants, 8.2 (95% Cl: 5.8-10.6) for partial participants and 5.3 (95% Cl: 3.6-6.9) for complete non-responders. Other urologic diagnoses followed the same pattern. However, age-adjusted prevalence rates for general medical examination history and major non-urologic morbidities were decidedly similar across response groups. Conclusions. These data suggest response may have been driven, in part, by concerns about urologic disease However, the similarity in non-urologic diagnoses and general medical examinations provide some preliminary reassurance that the 55% response rate did not necessarily compromise generalizabllity.

Original languageEnglish (US)
Pages (from-to)1198-1205
Number of pages8
JournalInternational journal of epidemiology
Volume23
Issue number6
DOIs
StatePublished - Dec 1994
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology

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