The natural history of patients with benign prostatic hyperplasia as diagnosed by North American urologists

M. J. Barry, Jr Fowler, L. Bin, J. C. Pitts, C. J. Harris, Jr Mulley, H. L. Holtgrewe

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: We defined outcomes for men with a clinical diagnosis of benign prostatic hyperplasia. Materials and Methods: We followed for 4 years 500 candidates for elective prostatectomy treated nonoperatively in 5 North American urology practices. Results: There were 371 survivors with complete data at 4 years. Of 60 men with mild, 245 with moderate and 66 with severe baseline symptoms 10, 24 and 39%, respectively, had undergone surgery; 27, 31 and 27%, respectively, were on pharmacological therapy, and 63, 45 and 33%, respectively, were off active treatment at 4 years. Mild or moderate symptoms were noted at 4 years in 83, 59 and 23% of the patients, respectively, while 17, 41 and 77%, respectively, had severe symptoms or had undergone surgery. Conclusions: Outcomes for men with a clinical diagnosis of benign prostatic hyperplasia depend on initial symptom severity. However, the course of symptoms also varies among patients even with the same initial symptom severity.

Original languageEnglish (US)
Pages (from-to)10-15
Number of pages6
JournalJournal of Urology
Volume157
Issue number1
DOIs
StatePublished - Jan 1997

Keywords

  • prognosis
  • prostatectomy
  • prostatic hypertrophy
  • urinary retention

ASJC Scopus subject areas

  • Urology

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