TY - JOUR
T1 - The natural history of isolated left ventricular diastolic dysfunction
AU - Brogan, Walter C.
AU - Hillis, L. David
AU - Flores, Eduardo D.
AU - Lange, Richard A.
PY - 1992
Y1 - 1992
N2 - study objective: To assess the natural history of isolated left ventricular diastolic dysfunction. materials and methods: Follow-up (average duration, 68 months) was obtained in 51 patients with isolated left ventricular diastolic dysfunction at cardiac catheterization, characterized by (1) an elevated left ventricular end-diastolic pressure; (2) normal left ventricular end-diastolic and end-systolic volumes; (3) normal left ventricular ejection fraction; (4) no coronary artery disease; and (5) no valvular disease. results: During follow-up, seven patients died, but only one died of cardiac causes. Of the 44 living subjects, 20 (45%) noted new-onset symptoms of congestive heart failure, with 11 (25%) of these requiring hospitalization, and 12 (27%) required hospitalization for recurrent chest pain. conclusion: Isolated left ventricular diastolic dysfunction is associated with a low cardiac mortality; at the same time, however, it is associated with substantial morbidity.
AB - study objective: To assess the natural history of isolated left ventricular diastolic dysfunction. materials and methods: Follow-up (average duration, 68 months) was obtained in 51 patients with isolated left ventricular diastolic dysfunction at cardiac catheterization, characterized by (1) an elevated left ventricular end-diastolic pressure; (2) normal left ventricular end-diastolic and end-systolic volumes; (3) normal left ventricular ejection fraction; (4) no coronary artery disease; and (5) no valvular disease. results: During follow-up, seven patients died, but only one died of cardiac causes. Of the 44 living subjects, 20 (45%) noted new-onset symptoms of congestive heart failure, with 11 (25%) of these requiring hospitalization, and 12 (27%) required hospitalization for recurrent chest pain. conclusion: Isolated left ventricular diastolic dysfunction is associated with a low cardiac mortality; at the same time, however, it is associated with substantial morbidity.
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U2 - 10.1016/0002-9343(92)90781-6
DO - 10.1016/0002-9343(92)90781-6
M3 - Article
C2 - 1605144
AN - SCOPUS:0026762958
SN - 0002-9343
VL - 92
SP - 627
EP - 630
JO - American Journal of Medicine
JF - American Journal of Medicine
IS - 6
ER -