The natural history of IgE-mediated cow's milk allergy

Justin M. Skripak, Elizabeth C. Matsui, Kim Mudd, Robert A Wood

Research output: Contribution to journalArticle

Abstract

Background: Cow's milk allergy (CMA) is the most common food allergy in infants and young children, affecting 2% to 3% of the general population. Most studies have shown the prognosis of developing tolerance to cow's milk to be good, with most outgrowing their allergy by age 3 years. Objective: To define the natural course of CMA and identify the factors that best predict outcome in a large referral population of children with CMA. Methods: Clinical history, test results, and final outcome were collected on 807 patients with IgE-mediated CMA. Patients were considered tolerant after they passed a challenge or experienced no reactions in the past 12 months and had a cow's milk IgE (cm-IgE) level

Original languageEnglish (US)
Pages (from-to)1172-1177
Number of pages6
JournalThe Journal of Allergy and Clinical Immunology
Volume120
Issue number5
DOIs
StatePublished - Nov 2007

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Keywords

  • Cow's milk
  • food allergy
  • IgE
  • prognosis
  • tolerance

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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