The natural history, current status, and future trends of HIV infection.

M. K. Lears, K. S. Alwood

Research output: Contribution to journalReview article


Nearly 50 million people worldwide have been infected with human immunodeficiency virus (HIV), and an estimated 12 to 13 million children have been orphaned by the acquired immune deficiency syndrome (AIDS) epidemic. The natural history of HIV infection continues to evolve as researchers and clinicians unearth new facts about the virus and develop new treatment regimens for patients. The status of anti-HIV treatments is never static but constantly changing. Patients and providers struggle with adherence issues. Vaccine development, viewed as an essential step in controlling the epidemic, is complicated by the genetic diversity of the virus and the inability of the body to clear the virus. Tremendous strides have occurred in the HIV/AIDS arena, yet daunting challenges remain. This overview article presents the natural history, the current status, and future trends of HIV infection.

Original languageEnglish (US)
Pages (from-to)1-19
Number of pages19
JournalLippincott's primary care practice
Issue number1
StatePublished - Jan 1 2000


ASJC Scopus subject areas

  • Medicine(all)

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