The national academy of clinical biochemistry laboratory medicine evidence-based practice guidelines for point of care testing in evaluation of renal analytes

Abdulrahman S. Alzahrani, William Clarke

Research output: Contribution to journalArticle

Abstract

The National Academy of Clinical Biochemistry (NACB) has recently published evidence-based clinical practice guidelines for renal function testing at the point of care. For many of the clinical questions considered, no recommendations were made because there was not sufficient evidence to recommend for or against point-of-care testing (POCT) in the various clinical scenarios. There was sufficient evidence to recommend using POCT for measurement of serum urea nitrogen and creatinine in outpatient settings (cardiovascular diagnostics laboratory) based on evidence that it led to improved patient outcomes. However, POCT for the same analytes in the emergency department was recommended against based on lack of evidence that it significantly improved patient outcomes. The NACB also recommended against using dipstick urinalysis for proteinuria screening or evaluation of hypertensive pregnant women for preeclampsia because of insufficient evidence that POCT led to improved patient outcomes in either case. The NACB POCT guidelines represent the most comprehensive review of evidence in the literature to date; however, it is clear that much more work remains to be done to establish the utility of POCT for renal analytes in the context of evidence-based medicine.

Original languageEnglish (US)
Pages (from-to)261-264
Number of pages4
JournalPoint of Care
Volume6
Issue number4
DOIs
StatePublished - Dec 2007

Fingerprint

Evidence-Based Practice
Practice Guidelines
Biochemistry
Medicine
Kidney
Urinalysis
Evidence-Based Medicine
Pre-Eclampsia
Point-of-Care Testing
Proteinuria
Urea
Hospital Emergency Service
Pregnant Women
Creatinine
Outpatients
Nitrogen
Guidelines
Serum

Keywords

  • NACB
  • Point of care testing
  • Renal analytes

ASJC Scopus subject areas

  • Nursing(all)

Cite this

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abstract = "The National Academy of Clinical Biochemistry (NACB) has recently published evidence-based clinical practice guidelines for renal function testing at the point of care. For many of the clinical questions considered, no recommendations were made because there was not sufficient evidence to recommend for or against point-of-care testing (POCT) in the various clinical scenarios. There was sufficient evidence to recommend using POCT for measurement of serum urea nitrogen and creatinine in outpatient settings (cardiovascular diagnostics laboratory) based on evidence that it led to improved patient outcomes. However, POCT for the same analytes in the emergency department was recommended against based on lack of evidence that it significantly improved patient outcomes. The NACB also recommended against using dipstick urinalysis for proteinuria screening or evaluation of hypertensive pregnant women for preeclampsia because of insufficient evidence that POCT led to improved patient outcomes in either case. The NACB POCT guidelines represent the most comprehensive review of evidence in the literature to date; however, it is clear that much more work remains to be done to establish the utility of POCT for renal analytes in the context of evidence-based medicine.",
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