The multifaceted metabolism of glioblastoma

Addison Quinones; Anne Le

doi:10.1007/978-3-319-77736-8_4

The multifaceted metabolism of glioblastoma

Addison Quinones, Anne Le

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Glioblastoma (GBM) can be categorized into different subtypes based on diverse metabolic profiles.Characteristic genomic alterations lead to transformed metabolism.Synergistic therapies are beneficial to combat dynamic adaptations of glioblastoma metabolism. Advanced-grade brain tumors exhibit distinct metabolic profiles compared to lower-grade tumors.

Original language	English (US)
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer New York LLC
Pages	59-72
Number of pages	14
DOIs	https://doi.org/10.1007/978-3-319-77736-8_4
State	Published - 2018

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1063
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

Keywords

Cysteine catabolism
Glioblastoma
Glutamine metabolism
IDH1 mutation
Metabolic profile
mTOR signaling

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-3-319-77736-8_4

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abstract = "Glioblastoma (GBM) can be categorized into different subtypes based on diverse metabolic profiles.Characteristic genomic alterations lead to transformed metabolism.Synergistic therapies are beneficial to combat dynamic adaptations of glioblastoma metabolism. Advanced-grade brain tumors exhibit distinct metabolic profiles compared to lower-grade tumors.",

keywords = "Cysteine catabolism, Glioblastoma, Glutamine metabolism, IDH1 mutation, Metabolic profile, mTOR signaling",

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KW - Glioblastoma

KW - Glutamine metabolism

KW - IDH1 mutation

KW - Metabolic profile

KW - mTOR signaling

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The multifaceted metabolism of glioblastoma

Abstract

Publication series

Keywords

ASJC Scopus subject areas

Access to Document

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