The multifaceted metabolism of glioblastoma

Addison Quinones, Anne Le

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Glioblastoma (GBM) can be categorized into different subtypes based on diverse metabolic profiles.Characteristic genomic alterations lead to transformed metabolism.Synergistic therapies are beneficial to combat dynamic adaptations of glioblastoma metabolism. Advanced-grade brain tumors exhibit distinct metabolic profiles compared to lower-grade tumors.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages59-72
Number of pages14
DOIs
StatePublished - 2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1063
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Cysteine catabolism
  • Glioblastoma
  • Glutamine metabolism
  • IDH1 mutation
  • Metabolic profile
  • mTOR signaling

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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