The microbicide tenofovir does not inhibit nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine samples

Billie Jo Wood, Patricia Rizzo-Price, Jeff Holden, Andrew Hardick, Thomas C. Quinn, Charlotte A. Gaydos

Research output: Contribution to journalArticlepeer-review

Abstract

The potential inhibitory effects of tenofovir and a placebo were examined using the Becton Dickinson ProbeTec, Gen-Probe Aptima Combo 2, and Roche Amplicor tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae. Concentrations of 5% to 0% of tenofovir and the placebo were added to dilutions of C. trachomatis and N. gonorrhoeae. No appreciable inhibition was observed.

Original languageEnglish (US)
Pages (from-to)763-765
Number of pages3
JournalJournal of clinical microbiology
Volume46
Issue number2
DOIs
StatePublished - Feb 2008

ASJC Scopus subject areas

  • Microbiology (medical)

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