@inbook{125c3db332934a698ea74c00662aea4b,
title = "The metabolism of renal cell carcinomas and liver cancer",
abstract = "Different oncogenic mutations lead to different metabolic phenotypes in renal cell carcinomas (RCC).Loss of the von Hippel-Lindau (VHL) tumor suppressor gene results in metabolic alterations including aerobic glycolysis in RCC.Fumarate hydratase mutations result in an increase in aerobic glycolysis in RCC.Different oncogenic mutations lead to different metabolic phenotypes in primary liver cancer.MYC and MET mutations regulate glucose and glutamine differently in primary liver cancer.Glucose metabolism increased by acetylated phosphoglycerate kinase 1 (PGK1) leads to the promotion of cancer cell proliferation and tumorigenesis in the liver.",
keywords = "Glucose metabolism, Glutamine metabolism, Metabolic phenotypes, Oncogenic heterogeneity, Primary liver cancer, Renal cell carcinoma",
author = "Tu Nguyen and Anne Le",
note = "Publisher Copyright: {\textcopyright} 2018, Springer International Publishing AG, part of Springer Nature.",
year = "2018",
doi = "10.1007/978-3-319-77736-8_8",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "107--118",
booktitle = "Advances in Experimental Medicine and Biology",
}