The mesial-temporal lobe and autism: Case report and review

Research output: Contribution to journalArticle

Abstract

Human and non-human primate research has shown that pathological processes affecting the temporal lobe, particularly the amygdala and hippocampus, are related to the development of the autistic syndrome. This case report describes a young male child with left temporal oligodendroglioma, who demonstrated a constellation of autistic behaviors meeting DSM-III-R criteria for pervasive developmental disorder. Abnormalities in social interaction, affective expression and communication were particularly evident. Some of the symptoms improved after tumor resection, while other signs of qualitative abnormalities in development emerged or persisted. This case adds evidence to the hypothesis that damage to mesial-temporal structures at an early developmental period may lead to the autistic syndrome.

Original languageEnglish (US)
Pages (from-to)252-259
Number of pages8
JournalDevelopmental Medicine and Child Neurology
Volume34
Issue number3
StatePublished - 1992

Fingerprint

Temporal Lobe
Autistic Disorder
Oligodendroglioma
Pathologic Processes
Interpersonal Relations
Amygdala
Diagnostic and Statistical Manual of Mental Disorders
Primates
Hippocampus
Communication
Research
Neoplasms

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

The mesial-temporal lobe and autism : Case report and review. / Hoon, Alexander Holliday; Reiss, A. L.

In: Developmental Medicine and Child Neurology, Vol. 34, No. 3, 1992, p. 252-259.

Research output: Contribution to journalArticle

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