The membrane receptor mediated signal transduction mechanism of low intensity light induced apoptosis

Timon Cheng Yi Liu, Jian Ling Jiao, Ling Zhu, Duan Rui, Xiao Yang Xu, Song Hao Liu

Research output: Contribution to journalConference articlepeer-review

Abstract

Much research showed that there is phtotobiomodulation on cell apoptosis. The membrane receptor mediated signal transduction mechanism (STM) on photobiomodulation was suggested by Liu et al, and verified by successful applications. In this paper, it was used to study photobiomodulation on cell apoptosis. As the frequency of the absorption light of membrane receptors is greater than the visible light, the membrane absorption of the light is non-resonant, and its transition rate is extraordinarily small, but can be amplified by the coherent state of the identical and independent membrane receptors. The activation coherent states of receptors will activate signal transduction pathway, which was called collective phototransduction. It was shown that collective phototransduction mediated STM was one of the possible mechanisms of photobiomodulation on cell apoptosis.

Original languageEnglish (US)
Pages (from-to)170-175
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5254
StatePublished - Dec 1 2003
EventThird International Conference on Photonics and Imaging in Biology and Medicine - Wuhan, China
Duration: Jun 8 2003Jun 11 2003

Keywords

  • Apoptosis
  • Low intensity laser
  • Photobiomodulation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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