The mechanism and consequences of retrotransposition

Gerald R. Fink; Jef D. Boeke; David J. Garfinkel

doi:10.1016/0168-9525(86)90200-3

The mechanism and consequences of retrotransposition

Gerald R. Fink, Jef D. Boeke, David J. Garfinkel

School of Medicine

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Ty elements are repeated DNA sequences in yeast that move around the genome through a surprising sequence of events. The element is transcribed into RNA and this RNA is reverse-transcribed into a DNA copy capable of inserting itself into many different chromosomal locations. The presence of reverse transcriptase in cells raises the possibility that reverse transcription has a role in normal cellular processes.

Original language	English (US)
Pages (from-to)	118-123
Number of pages	6
Journal	Trends in Genetics
Volume	2
Issue number	C
DOIs	https://doi.org/10.1016/0168-9525(86)90200-3
State	Published - 1986

ASJC Scopus subject areas

Genetics

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10.1016/0168-9525(86)90200-3

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title = "The mechanism and consequences of retrotransposition",

abstract = "Ty elements are repeated DNA sequences in yeast that move around the genome through a surprising sequence of events. The element is transcribed into RNA and this RNA is reverse-transcribed into a DNA copy capable of inserting itself into many different chromosomal locations. The presence of reverse transcriptase in cells raises the possibility that reverse transcription has a role in normal cellular processes.",

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year = "1986",

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AU - Boeke, Jef D.

AU - Garfinkel, David J.

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AB - Ty elements are repeated DNA sequences in yeast that move around the genome through a surprising sequence of events. The element is transcribed into RNA and this RNA is reverse-transcribed into a DNA copy capable of inserting itself into many different chromosomal locations. The presence of reverse transcriptase in cells raises the possibility that reverse transcription has a role in normal cellular processes.

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DO - 10.1016/0168-9525(86)90200-3

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JO - Trends in Genetics

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The mechanism and consequences of retrotransposition

Abstract

ASJC Scopus subject areas

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