The melanotic and amelanotic transplanted hamster melanoma (Fortner) has been grown in tissue culture. Four main cell types are observed; the melanocyte, fibrocyte, macrophage, and an unusual form of giant fibrocytic cell. The latter often attains a diameter of 102 μ and can be seen to contain intact melanocytes within its cytoplasm. It is demonstrated that these melanocytes are ingested and subsequently disintegrate within the giant cell. This cell type has previously been noted in histologic preparations of human melanomas. It has not previously been described in tissue culture.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jun 1 1961|
ASJC Scopus subject areas
- Cancer Research