The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1- binding activity through caspase activation in neurons

Medicine & Life Sciences

• 3-nonenal 100%
• 4-hydroxy-2-nonenal 76%
• Transcription Factor AP-1 63%
• Caspases 58%
• Protein Binding 57%
• Neurons 35%
• Caspase Inhibitors 20%
• Calcium 15%
• DNA 9%
• benzyloxycarbonyl-valyl-alanyl-aspartic acid 9%
• Replication Protein C 8%
• Phosphotransferases 8%
• Homeostasis 8%
• Calcium Chelating Agents 8%
• 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid 8%
• Phosphorylation 7%
• Ruthenium Red 7%
• Ketones 7%
• Apoptosis 7%
• Aldehydes 6%
• JNK Mitogen-Activated Protein Kinases 6%
• DNA-Binding Proteins 6%
• Membrane Lipids 6%
• Cycloheximide 6%
• Esters 5%
• Cyclosporine 5%
• Caspase 3 5%
• Permeability 4%
• Cell Death 4%
• Transcription Factors 4%
• Membranes 3%
• Wounds and Injuries 2%
• Genes 2%

Chemical Compounds

• Calcium(0) 44%
• Lipid 39%
• Excitotoxicity 20%
• Ruthenium Red 16%
• Cyclosporin A 15%
• Cycloheximide 15%
• Apoptotic 13%
• Cell Death 12%
• Chelating Agent 11%
• Permeability 9%
• Ester 7%
• Protein 4%