The link between allergy and Menière's disease

Heather M. Weinreich, Yuri Agrawal

Research output: Contribution to journalReview articlepeer-review


PURPOSE OF REVIEW: To examine evidence supporting the association of allergy and Menière's disease. RECENT FINDINGS: Animal studies have shown evidence that a provoked systemic immune challenge can result in an allergic reaction within the inner ear, whereas premedication with leukotriene antagonists can prevent the development of endolymphatic hydrops. In human subjects, further data support a heightened allergic response in patients with Menière's disease, whereas pharmacological treatments that target histamine receptors help to control vertiginous symptoms. However, the relationship of migraine with a history of allergy and Menière's disease may confound this association. SUMMARY: Although the evidence of a causal association between allergy and Menière's disease is inconclusive, the inclusion of allergy control as part of the treatment plan for Menière's disease is low risk to the patient and should be considered for patients with indications that include history of seasonal or food allergy, childhood or family history of allergy, bilateral Menière's symptoms, or a development of symptoms within a short time after exposure of food or inhaled allergen.

Original languageEnglish (US)
Pages (from-to)227-230
Number of pages4
JournalCurrent Opinion in Otolaryngology and Head and Neck Surgery
Issue number3
StatePublished - Jun 2014


  • Allergy
  • Menière's disease
  • endolymphatic hydrops

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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