The limitless applications of single-cell metabolomics

Shenghao Guo, Cissy Zhang, Anne Le

Research output: Contribution to journalReview articlepeer-review


Single-cell metabolomics (SCM) is currently one of the most powerful tools for performing high-throughput metabolic analysis at the cellular level. The power of single-cell metabolomics to determine the metabolic profiles of individual cells makes it very suitable for decoding cell heterogeneity. SCM bears great potential in cell type identification and differentiation within cell colonies. With the development of various equipment and techniques, SCM analysis has become possible for a wide range of biological samples. Many fields have incorporated this cutting-edge analytic tool to generate fruitful findings. This review article pays close attention to the prevalent techniques utilized in SCM and the exciting new findings and applications developed by studies in phytology, neurology, and oncology using SCM.

Original languageEnglish (US)
Pages (from-to)115-122
Number of pages8
JournalCurrent Opinion in Biotechnology
StatePublished - Oct 2021

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering


Dive into the research topics of 'The limitless applications of single-cell metabolomics'. Together they form a unique fingerprint.

Cite this