The keratopathy of Crohn's disease

D. L. Knox, R. C. Snip, W. J. Stark

Research output: Contribution to journalArticlepeer-review


A distinctive subepithelial keratopathy developed in four adult patients with Crohn's disease (granulomatous ileocolitis). Small, bilateral, symmetrical subepithelial, and anterior proliferative infiltrates and scarring were present 2 to 3 mm inside the entire corneoscleral limbus. Vision was not affected because the lesions spared the central cornea. The mechanism is not known and the lesion should be regarded as a distinct clinical sign of Crohn's disease.

Original languageEnglish (US)
Pages (from-to)862-865
Number of pages4
JournalAmerican journal of ophthalmology
Issue number6
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Ophthalmology

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