The intramolecular nitrile oxide cycloaddition route to spirocyclic alkaloids. A total synthesis of isonitramine and sibirine

Alan P. Kozikowski, P. W. Yuen

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

The intramolecular nitrile oxide cycloaddition reaction has been found to accommodate the construction of spirocycles in modest yield as revealed by a synthesis of the title alkaloids.

Original languageEnglish (US)
Pages (from-to)847-848
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number13
DOIs
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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