The ins and outs of iron homeostasis

Adriana Donovan, Cindy N. Roy, Nancy C. Andrews

Research output: Contribution to journalReview articlepeer-review

58 Scopus citations


Iron is an essential element that is toxic when it accumulates in excess. Intricate regulatory mechanisms have evolved to maintain iron homeostasis within cells and between different tissues of complex organisms. This review discusses the proteins involved in iron transport and storage and their regulation in health and disease.

Original languageEnglish (US)
Pages (from-to)115-123
Number of pages9
Issue number2
StatePublished - Apr 2006
Externally publishedYes

ASJC Scopus subject areas

  • Physiology


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