The Inheritance of Gilles de la Tourette's Syndrome

Roswell Eldridge, Martha B. Denckla, Haggai Hermesh, Dov Atzenberg, Margo Lapidot, Hanan Munitz, David L. Pauls, James F. Leckman

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: Pauls and Leckman conclude that Gilles de la Tourette's syndrome, as defined by them, is inherited as an autosomal dominant trait (Oct. 16 issue).1 On the basis of this conclusion, they indicate that “the next step in understanding the genetics of Tourette's syndrome will be to try to establish a linkage relation between a marker and the hypothetical gene for the disease.” We would like to repeat a note of caution2 before the race for the hypothetical gene is joined by all other interested parties. A major unresolved issue, particularly in family studies, concerns the definition of…

Original languageEnglish (US)
Pages (from-to)1346-1348
Number of pages3
JournalNew England Journal of Medicine
Volume316
Issue number21
DOIs
StatePublished - May 21 1987
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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