The infant microbiome development

Mom matters

Noel Mueller, Elizabeth Bakacs, Joan Combellick, Zoya Grigoryan, Maria G. Dominguez-Bello

Research output: Contribution to journalArticle

Abstract

The infant microbiome plays an essential role in human health and its assembly is determined by maternal-offspring exchanges of microbiota. This process is affected by several practices, including Cesarean section (C-section), perinatal antibiotics, and formula feeding, that have been linked to increased risks of metabolic and immune diseases. Here we review recent knowledge about the impacts on infant microbiome assembly, discuss preventive and restorative strategies to ameliorate the effects of these impacts, and highlight where research is needed to advance this field and improve the health of future generations.

Original languageEnglish (US)
Pages (from-to)109-117
Number of pages9
JournalTrends in Molecular Medicine
Volume21
Issue number2
DOIs
StatePublished - Feb 1 2015
Externally publishedYes

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Microbiota
Child Development
Metabolic Diseases
Immune System Diseases
Social Responsibility
Health
Cesarean Section
Mothers
Anti-Bacterial Agents
Research

ASJC Scopus subject areas

  • Molecular Biology
  • Molecular Medicine

Cite this

Mueller, N., Bakacs, E., Combellick, J., Grigoryan, Z., & Dominguez-Bello, M. G. (2015). The infant microbiome development: Mom matters. Trends in Molecular Medicine, 21(2), 109-117. https://doi.org/10.1016/j.molmed.2014.12.002

The infant microbiome development : Mom matters. / Mueller, Noel; Bakacs, Elizabeth; Combellick, Joan; Grigoryan, Zoya; Dominguez-Bello, Maria G.

In: Trends in Molecular Medicine, Vol. 21, No. 2, 01.02.2015, p. 109-117.

Research output: Contribution to journalArticle

Mueller, N, Bakacs, E, Combellick, J, Grigoryan, Z & Dominguez-Bello, MG 2015, 'The infant microbiome development: Mom matters', Trends in Molecular Medicine, vol. 21, no. 2, pp. 109-117. https://doi.org/10.1016/j.molmed.2014.12.002
Mueller N, Bakacs E, Combellick J, Grigoryan Z, Dominguez-Bello MG. The infant microbiome development: Mom matters. Trends in Molecular Medicine. 2015 Feb 1;21(2):109-117. https://doi.org/10.1016/j.molmed.2014.12.002
Mueller, Noel ; Bakacs, Elizabeth ; Combellick, Joan ; Grigoryan, Zoya ; Dominguez-Bello, Maria G. / The infant microbiome development : Mom matters. In: Trends in Molecular Medicine. 2015 ; Vol. 21, No. 2. pp. 109-117.
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